Theaimof this study was to evaluate complexes of L-ascorbyl palmitate (ASCP) and urea (UR). This evaluation involved differential\nscanning calorimetry (DSC), powder X-ray diffraction (PXRD), scanning electron microscopy (SEM), near-infrared spectroscopy\n(NIR), a solubility test, a 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging test, and a mushroom tyrosinase inhibition\nassay. Physicochemical evaluation revealed that ASCP/UR complexes form at a molar ratio of 1/12.The solubility test revealed that\nASCP/UR complexes had increased solubility compared to ASCP. The DPPH radical scavenging test and mushroom tyrosinase\ninhibition assay revealed that the activity of ASCP/UR complexes was not impaired by complex formation. These results are\nprobably due to the tetragonal crystal system of UR changing to a hexagonal crystal system and interaction with the alkyl group of\nASCP.
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